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Table 1 COPD/CB patient characteristics at baseline and medication during the year before baseline

From: Exacerbations and healthcare resource utilization among COPD patients in a Swedish registry-based nation-wide study

Patient characteristics Female
N = 47,487 (53.6%)
Male
N = 41,061 (46.4%)
P-value Total
N = 88,548 (100%)
Age, years 71.9 ± 11.1 72.3 ± 10.5 <0.001 72.1 ± 10.8
Time since COPD/CB diagnosis, years 4.5 ± 3.2 4.3 ± 3.2 <0.001 4.4 ± 3.2
COPD medicationa
 SABA 1299 (2.7) 957 (2.3) <0.001 2256 (2.5)
 SAMA 1025 (2.2) 905 (2.2) 0.660 1930 (2.2)
 SABA + SAMA 353 (0.7) 260 (0.6) 0.054 613 (0.7)
 ICS only 3510 (7.4) 2561 (6.2) <0.001 6071 (6.9)
 LABA only 667 (1.4) 562 (1.4) 0.670 1229 (1.4)
 LAMA only 2687 (5.7) 2504 (6.1) 0.006 5191 (5.9)
 ICS + LABA 12,275 (25.8) 9644 (23.5) <0.001 21,919 (24.8)
 ICS + LAMA 1181 (2.5) 913 (2.2) 0.011 2094 (2.4)
 LABA + LAMA 434 (0.9) 369 (0.9) 0.839 803 (0.9)
 ICS + LABA + LAMA 12,197 (25.7) 9553 (23.3) <0.001 21,750 (24.6)
No COPD medication 11,859 (25.0) 12,833 (31.3) <0.001 24,692 (27.9)
Other medications
 Beta blockers 16,375 (34.5) 16,430 (40.0) <0.001 32,805 (37.0)
 ACE inhibitors 11,757 (24.8) 13,309 (32.4) <0.001 25,066 (28.3)
 Calcium blockers 10,423 (21.9) 8808 (21.5) 0.074 19,231 (21.7)
 Angiotensin-receptor blockers 6106 (12.9) 5247 (12.8) 0.731 11,353 (12.8)
 Statins 13,105 (27.6) 14,327 (34.9) <0.001 27,432 (31.0)
  1. Numbers presented as n (%), or mean ± SD. P-value for difference between genders
  2. Abbreviations: COPD Chronic obstructive pulmonary disease, CB Chronic bronchitis, SD Standard deviation, SABA Inhaled short-acting beta-2-agonist, SAMA Inhaled short-acting muscarinic antagonist, ICS Inhaled glucocorticoids, LABA Long-acting beta agonist, LAMA Long-acting muscarinic antagonist, ACE Angiotensin-converting enzyme
  3. aResults for SABA and/or SAMA are reported as monotherapy without any other COPD medication allowed. Use of rescue medication (SABA and/or SAMA) was ignored when evaluating usage percentages of other COPD medication options. ATC codes are listed in Additional file 1: Table S1