From: Morbidity and mortality related to pneumonia and TRACHEOBRONCHITIS in ICU after lung transplantation
Variable | Total population (n = 175) | Patients without BRI (n = 14) | Patients with BRI (n = 161) | *p | patients with pneumonia (n = 34) | Patients with tracheobronchitis without any episode of pneumonia (n = 127) | *p |
---|---|---|---|---|---|---|---|
Age, year, median [IQR] | 57 [50–60] | 60 [55–63] | 57 [50–60] | 0.016 | 56 [50–59] | 57 [49–60] | 0.84 |
Male gender, n (%) | 118 (67) | 6 (42) | 112 (69) | 0.07 | 24 (71) | 88 (69) | 1 |
Underlying lung disease, n (%) | |||||||
Emphysema/COPD | 70 (40) | 5 (36) | 65 (40) | 0.78 | 14 (41) | 51 (40) | 1 |
Idiopathic pulmonary fibrosis | 66 (38) | 7(50) | 59 (37) | 0.39 | 9 (27) | 50 (39) | 0.23 |
Other | 39 (22) | 2 (14) | 37 (23) | 0.74 | 11 (32) | 26 (21) | 0.17 |
Transplantation type, n (%) | |||||||
Single lung | 125 (71) | 13 (92) | 112 (69) | 0.07 | 20 (59) | 92 (72) | 0.4 |
Double | 50 (29) | 1 (8) | 49 (31) | 0.1 | 14 (41) | 35 (28) | 0.14 |
SAPS II, median [IQR] | 35 [29–42] | 32 [28–36] | 35 [29–42] | 0.34 | 37 [32–48] | 35 [28–42] | 0.09 |
SOFA | 5 [3–8] | 4 [3–6] | 5 [3–8] | 0.41 | 7 [4–10] | 5 [3–7] | 0.06 |
ECLS, n (%) | 30 (17) | 2 (14) | 28 (17) | 0.76 | 12 (35) | 16 (13) | 0.004 |
Primary graft dysfunction, n (%) | 12 (7) | 1 (7) | 11 (7) | 0.96 | 2 (6) | 9 (7) | 0.06 |
Donor colonization prior to LT, n (%) | 47 (42) | 3 (21) | 44 (27) | 0.76 | 9 (47) | 35 (42) | 0.8 |
One micro-organism | 39 (83) | 2 (67) | 37 (84) | 0.4 | 8 (89) | 29 (83) | 1 |
More than one micro-organism | 8 (17) | 1 (33 | 7 (16) | 0.4 | 1 (11) | 6 (17) | 1 |
Recipient colonization prior to LT, n (%) | 55 (38) | 8 (61) | 47 (36) | 0.08 | 10 (34) | 37 (36) | 1 |
One micro-organism | 35 (64) | 6 (75) | 29 (62) | 0.7 | 6 (60) | 23 (62) | 1 |
More than one micro-organism | 20 (36) | 2 (25) | 18 (38) | 0.7 | 4 (40) | 14 (38) | 1 |