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Table 6 uni- and multivariate analysis of the risk factors of mortality at one year after LT

From: Morbidity and mortality related to pneumonia and TRACHEOBRONCHITIS in ICU after lung transplantation

 

Univariate analysis

 

Multivariate analysis

 

Risk factors

Unadjusted Odds Ratio [95% CI]

*P value

Adjusted Odds Ratio [95% CI]

*P value

Pneumonia

5.9 [2.7–13.3]

< 0.0001

7.1 [2.7–18.7]

< 0.0001

BRI

0.5[0.2–1.6]

0.24

MRSA-MSSA BRI

0.9 [0.4–2.0]

1

NFGNB BRI

1.6 [0.8–3.1]

0.2

Age > 60 yo

1.8 [0.9–3.6]

0.14

3.0 [1.3–7.3]

0.013

Double LT

1.4 [0.7–2.8]

0.46

Idiopathic fibrosis

0.6 [0.3–1.2]

0.17

PGD

3.1 [1–9.8]

0.05

2.9 [0.7–12.6]

0.14

ECLS

0.7 [0.3–1.7]

0.5

MV > 14 days

6.6 [3.2–13.9]

< 0.0001

5.1 [2.2–11.8]

< 0.0001

SOFA > 5

1.2 [0.6–2.4]

0.6

SAPSII > 35

1.1 [0.6–2.1]

0.9

Apache 2 > 16

0.5 [0.3–1.0]

0.06

0.5 [0,2–1,3]

0.15

  1. *p < 0.05 was considered statistically significant. BRI = bacterial respiratory infections; MSSA = methicillin-susceptible Staphylococcus aureus; MRSA = methicillin-resistant Staphylococcus aureus; NFGNB = non-fermenting Gram-negative bacilli; LT = lung transplantation; PGD = primary graft dysfunction; ECLS = extracorporeal lung support; MV = mechanical ventilation; SOFA = Sequential Organ Failure Assessment; SAPSII = Simplified Acute Physiology Score