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Table 6 uni- and multivariate analysis of the risk factors of mortality at one year after LT

From: Morbidity and mortality related to pneumonia and TRACHEOBRONCHITIS in ICU after lung transplantation

  Univariate analysis   Multivariate analysis  
Risk factors Unadjusted Odds Ratio [95% CI] *P value Adjusted Odds Ratio [95% CI] *P value
Pneumonia 5.9 [2.7–13.3] < 0.0001 7.1 [2.7–18.7] < 0.0001
BRI 0.5[0.2–1.6] 0.24
MRSA-MSSA BRI 0.9 [0.4–2.0] 1
NFGNB BRI 1.6 [0.8–3.1] 0.2
Age > 60 yo 1.8 [0.9–3.6] 0.14 3.0 [1.3–7.3] 0.013
Double LT 1.4 [0.7–2.8] 0.46
Idiopathic fibrosis 0.6 [0.3–1.2] 0.17
PGD 3.1 [1–9.8] 0.05 2.9 [0.7–12.6] 0.14
ECLS 0.7 [0.3–1.7] 0.5
MV > 14 days 6.6 [3.2–13.9] < 0.0001 5.1 [2.2–11.8] < 0.0001
SOFA > 5 1.2 [0.6–2.4] 0.6
SAPSII > 35 1.1 [0.6–2.1] 0.9
Apache 2 > 16 0.5 [0.3–1.0] 0.06 0.5 [0,2–1,3] 0.15
  1. *p < 0.05 was considered statistically significant. BRI = bacterial respiratory infections; MSSA = methicillin-susceptible Staphylococcus aureus; MRSA = methicillin-resistant Staphylococcus aureus; NFGNB = non-fermenting Gram-negative bacilli; LT = lung transplantation; PGD = primary graft dysfunction; ECLS = extracorporeal lung support; MV = mechanical ventilation; SOFA = Sequential Organ Failure Assessment; SAPSII = Simplified Acute Physiology Score