Serum (1→3)-β-D-glucan and galactomannan levels in patients with cystic fibrosis: a retrospective cohort study

BMC Pulmonary Medicine

Table 4 Multivariate analysis with FEV1_predicted at serum sampling as dependent variable

Independent variables	Regression coefficient	p-value	R² corr.	Effect size f
Age	−0.073	0.772	52.6%	1.05 (strong effect)
BDG	−0.098	0.002
Persistent A. fumigatus detection	−2.951	0.562
A. fumigatus-specific IgE level	0.045	0.810
S. aureus detection	16.337	0.011
P. aeruginosa detection	−13.628	0.023
WBC	−2.911	< 0.001
CRP	−0.015	0.933
Systemic antibiotic therapy within the last 12 month	− 1.939	0.115
Nebulized antibiotic within the last 12 month	0.890	0.832

FEV1 forced expiratory volume in 1 s, BDG (1→3)-β-D-glucan, WBC white blood cell count, CRP C-reactive protein, R² coefficient of determination

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