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Table 7 Adjusted odds ratios (ORs) for the presence of peripheral vascular dysfunction by tertiles of FEV1% predicted and by smoking

From: Relationship between pulmonary function and peripheral vascular function in older Chinese: Guangzhou biobank cohort study-CVD

 

FEV1% predicted (%)

P for trend

Tertile 1

Tertile 2

Tertile 3

Non-smoker

 Range, %

> 104.1

91.4–104.1

< 91.4

 

 Number of participants

344

344

345

 

 Presence of arterial stiffness, n (%)

181 (53.6)

211 (61.3)

230 (66.7)

 

 Crude OR (95% CI)

1.00

1.43 (1.06–1.93)*

1.80 (1.32–2.45)**

< 0.001

 Adjusted OR (95% CI)

1.00

1.44 (1.00–2.07)

1.35 (0.93–1.98)

0.10

 Presence of PAD, n (%)

2 (0.6)

7 (2.0)

8 (2.3)

 

 Crude OR (95% CI)

1.00

3.55 (0.73–17.22)

4.06 (0.86–19.26)

0.08

 Adjusted OR (95% CI)

1.00

3.41 (0.69–16.86)

3.85 (0.78–18.97)

0.11

Ever-smoker

 Range, %

> 99.4

85.4–99.4

< 85.4

 

 Number of participants

165

165

165

 

 Presence of arterial stiffness, n (%)

112 (67.9)

112 (67.9)

134 (81.2)

 

 Crude OR (95% CI)

1.00

1.00 (0.63–1.59)

2.05 (1.23–3.40)**

0.007

 Adjusted OR (95% CI)

1.00

1.13 (0.65–1.96)

2.09 (1.09–4.01)*

0.03

 Presence of PAD, n (%)

2 (1.2)

4 (2.4)

6 (3.6)

 

 Crude OR (95% CI)

1.00

2.02 (0.37–11.21)

3.08 (0.61–15.47)

0.16

 Adjusted OR (95% CI)

1.00

2.56 (0.38–17.28)

1.47 (0.21–10.11)

0.81

  1. FEV 1 forced expiratory volume in 1 s, PAD peripheral arterial disease
  2. Adjusted for age, sex, education, physical activity, waist circumference, diastolic blood pressure, triglycerides, fasting plasma glucose, chronic obstructive pulmonary disease, asthma and medications (aspirin and/or lipid lowering medication)
  3. Arterial stiffness: brachial-ankle pulse wave velocity (baPWV) ≥1400 cm/s
  4. PAD: ankle-brachial index (ABI) < 0.9
  5. P for smoking interaction: (1) Arterial stiffness: 0.50; (2) PAD: 0.69
  6. *:P < 0.05; **:P < 0.01