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Table 8 Adjusted odds ratios (ORs) for the presence of peripheral vascular dysfunction by tertiles of FVC% predicted and by smoking

From: Relationship between pulmonary function and peripheral vascular function in older Chinese: Guangzhou biobank cohort study-CVD

 

FVC% predicted (%)

P for trend

Tertile 1

Tertile 2

Tertile 3

Non-smoker

 Range, %

> 102.6

90.8–102.6

< 90.8

 

 Number of participants

344

344

345

 

 Presence of arterial stiffness, n (%)

176 (51.2)

204 (59.3)

242 (70.1)

 

 Crude OR (95% CI)

1.00

1.39 (1.03–1.88)*

2.24 (1.64–3.07)**

< 0.001

 Adjusted OR (95% CI)

1.00

1.17 (0.82–1.68)

1.37 (0.94–2.01)

0.10

 Presence of PAD, n (%)

4 (1.2)

4 (1.2)

9 (2.6)

 

 Crude OR (95% CI)

1.00

1.00 (0.25–4.03)

2.23 (0.77–6.49)

0.14

 Adjusted OR (95% CI)

1.00

0.91 (0.22–3.78)

2.09 (0.61–7.24)

0.20

Ever-smoker

 Range, %

> 100.0

87.0–100.0

< 87.0

 

 Number of participants

165

165

165

 

 Presence of arterial stiffness, n (%)

109 (66.1)

115 (69.7)

134 (81.2)

 

 Crude OR (95% CI)

1.00

1.18 (0.74–1.88)

2.22 (1.34–3.68)*

0.002

 Adjusted OR (95% CI)

1.00

1.07 (0.61–1.87)

1.98 (1.08–3.61)*

0.03

 Presence of PAD, n (%)

3 (1.8)

3 (1.8)

6 (3.6)

 

 Crude OR (95% CI)

1.00

1.00 (0.20–5.03)

2.04 (0.50–8.29)

0.29

 Adjusted OR (95% CI)

1.00

1.19 (0.22–6.54)

1.10 (0.23–5.05)

0.91

  1. FVC forced vital capacity, PAD peripheral arterial disease
  2. Adjusted for age, sex, education, physical activity, waist circumference, diastolic blood pressure, triglycerides, fasting plasma glucose, chronic obstructive pulmonary disease, asthma and medications (aspirin and/or lipid lowering medication)
  3. Arterial stiffness: brachial-ankle pulse wave velocity (baPWV) ≥1400 cm/s
  4. PAD: ankle-brachial index (ABI) < 0.9
  5. P for smoking interaction: (1) Arterial stiffness: 0.15; (2) PAD: 0.54
  6. *:P < 0.05; **:P < 0.01