Fig. 4
From: Inhibition of Shp2 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats
Shp2 inhibition reduces cardiomyocyte hypertrophy and normalized myocardial fibrosis in MCT-induced PAH. a Representative images of hematoxylin and eosin staining for cardiomyocyte hypertrophy. Scale bar = 50 μm. b Quantification of CSA (n = 6 for each group). c Representative images of Masson’s trichrome staining for detecting myocardial fibrosis (blue). Scale bar = 50 μm. d Quantification of myocardial fibrosis (n = 6 for each group). Data was presented as means ± standard deviation (SD), *** P < 0.001