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Table 1 Participant Characteristics

From: Oxygen versus air-driven nebulisers for exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial

 

Mean (SD)

P

Oxygen N=45a

Air N=45a

Age (years)

70·4 (10·3)

72·3 (8·3)

0.34

Age at diagnosis of COPD (years)

58·6 (12·1) N = 40

58·8 (12·2) N = 44

0.92

BMI (kg/m2)

27·2 (7·7)

25·5 (8·9)

0.33

Smoking pack years

39·3 (31·1)

51·2 (39·2)

0.11

FEV1 (L)

0·81 (0·33) N = 35

0·85 (0·31) N = 37

0.69

FEV1% predicted

35·0 (11·5) N = 35

34·0 (11·8) N = 37

0.73

mMRC

2·38 (1·09)

2·33 (1·04)

0.84

Baseline Transcutaneous Data

 PtCO2 (mmHg)

38·0 (7·7)

37·2 (6·8)

0.59

 SpO2 (%)

92·6 (2·4)

92·6 (2·3)

0.93

 Heart Rate (per minute)

89·6 (15·7)

87·0 (16·0)

0.89

Baseline capillary blood gas

 pH

7·42 (0·04) N = 43

7·44 (0·03) N = 41

0.11

 PcapCO2 (mmHg)

40·2 (7·0) N = 43

38·5 (5·9) N = 41

0.23

 

N/45 (%)

P

Oxygen

Air

Male

17 (38)

24 (53)

0.20

Ethnicity

  

0.49

 European

24 (53)

31 (69)

 

 Māori

7 (16)

4 (9)

 

 Pacific

5 (11)

4 (9)

 

 Other

9 (20)

6 (13)

 

Previous Ventilation (ever)

12 (27)

3 (7)

0.02

Previous Ventilation Type

  

0.03

 NIV

10 (22)

3 (7)

 

 Intubation

2 (4)

0 (0)

 

Previous hypercapnia

23 (51)

17 (38)

0.29

Home Oxygen

2 (4)

1 (2)

0.99

Home Nebulisers

5 (11)

12 (27)

0.10

Comorbidities

 Heart Failure

8 (18)

3 (7)

0.20

 Asthma

6 (13)

2 (4)

0.27

 Bronchiectasis

3 (7)

4 (9)

0.99

  1. COPD Chronic Obstructive Pulmonary Disease, BMI Body Mass Index, FEV1 Forced Expiratory Volume in 1 s at time of randomisation, mMRC Modified Medical Research Council dyspnea scale, PtCO2 Transcutaneous partial pressure of carbon dioxide, SpO2 peripheral oxygen saturation, PcapCO2 Capillary partial pressure of carbon dioxide, NIV non-invasive ventilation
  2. aUnless indicated