Action | Time | PtCO2 Mean (SD) | Oxygen minus air | P | |
---|---|---|---|---|---|
[N = 45 for each unless specified] | (95% CI) | ||||
Oxygen | Air | ||||
Baseline | 0 | 38·0 (7·7) | 37·2 (6·8) | ||
1st nebulisation | 5 | 39·9 (8·3) | 37·0 (7·1) | 2·10 (1·49 to 2·71) | < 0·001 |
6 | 40·1 (8·4) | 37·0 (7·1) | 2·24 (1·63 to 2·86) | < 0·001 | |
10 | 40·8 (8·6) | 37·2 (6·9) | 2·76 (2·15 to 3·37) | < 0·001 | |
15 | 41·1 (8·8) | 37·3 (6·9) | 2·97 (2·36 to 3·59) | < 0·001 | |
20 | 38·6 (7·8) | 37·0 (6·4)a | 0·86 (0·25 to 1·48) | 0·006 | |
2nd nebulisation | 25 | 40·5 (8·3) | 36·8 (6·8)b | 2·77 (2·15 to 3·39) | < 0·001 |
26 | 40·6 (8·4) | 36·8 (6·8)b | 2·88 (2·26 to 3·50) | < 0·001 | |
30 | 41·1 (8·5) | 37·1 (6·6)a | 3·20 (2·59 to 3·82) | < 0·001 | |
35 | 41·3 (8·6) | 37·3 (6·5)a | 3·31 (2·70 to 3·93) | < 0·001 | |
Observation period | 40 | 39·0 (8·1)a | 37·0 (6·7)a | 1·14 (0·52 to 1·76) | < 0·001 |
45 | 38·1 (7·5) | 36·7 (6·3)a | 0·61 (− 0·01 to 1·22) | 0·053 | |
50 | 37·9 (7·4) | 36·6 (6·2)a | 0·59 (− 0·02 to 1·21) | 0·059 | |
55 | 37·9 (7·3) | 36·6 (6·0)a | 0·51 (− 0·10 to 1·13) | 0·1 | |
60 | 37·9 (7·3) | 36·7 (6·1)a | 0·51 (− 0·10 to 1·13) | 0·1 | |
65 | 38·1 (7·2) | 36·7 (6·1)a | 0·63 (0·01 to 1·25) | 0·045 | |
70 | 37·5 (6·5)a | 36·7 (6·1)a | 0·60 (− 0·02 to 1·21) | 0·059 | |
75 | 37·8 (6·8) | 36·7 (6·1)a | 0·42 (− 0·20 to 1·03) | 0·18 | |
80 | 37·9 (6·9) | 36·7 (6·3)a | 0·40 (− 0·21 to 1·02) | 0·2 |