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Table 1 The mechanism of action for surfactant in ARDS

From: Effect of surfactant administration on outcomes of adult patients in acute respiratory distress syndrome: a meta-analysis of randomized controlled trials

The mechanism of action for surfactant

 The capacity to maintain lower alveolar tension and stability of alveolar volume

 Promotion of gas exchange and distribution

 Anti-action of edema in alveoli and interstitium

 Modulation of systemic inflammatory reactions in ARDS

 Reduction of local mechanical forces in ARDS