Fig. 5
From: CD147 increases mucus secretion induced by cigarette smoke in COPD
Changes in MUC5AC after CD147 silencing by siRNA transfection. CD147 protein (a) and mRNA (b) expression levels were assessed after siRNA transfection. Three CD147 siRNA were designed, and CD147 siRNA 1 was the most effective at silencing CD147 expression. *p < 0.05, compared with control transfection. MUC5AC secretion (c) and MUC5AC mRNA expression (d) were detected after CD147 silencing. **p < 0.05, compared with the control group, ***p < 0.05, compared with the 10% CS extract group. The results are representative of 3 independent experiments