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Table 1 Hospitalization rates for bronchiectasis (mean age-adjusted and other rates)

From: The economic burden of bronchiectasis – known and unknown: a systematic review

Reference

Dates, N

Results

Mean annual age-adjusted hospitalization rates

Bibby et al., 2015 [20] (New Zealand)

2008–2013

N = 5494

• 25.7 per 100,000 population (1° diagnosis)

Ringshausen et al., 2013 [21] (Germany)

2005–2011

N = 61,838

• 9.4 per 100,000 population (any diagnosis)

• 1.8 per 100,000 (1° diagnosis)

Sanchez-Munoz et al., 2016 [18] (Spain)

2004–2013

N = 70,676

• 15.5 per 100,000 population (1° diagnosis)

Seitz et al., 2010 [13] (USA)

1996–2006

N = 258,947

• 16.5 per 100,000 population (any diagnosis)

• 2.0 per 100,000 (1° diagnosis)

Hospitalization rates

Chan et al., 2013 [24] (New Zealand)

2001–2008

N = 100

• Mean annual hospitalization rate per patient: 1.29

de Costa et al., 2015 [25] (Portugal)

2013–2014

N = 70

• Mean annual hospitalization rate per patient: 0.8

Hwang et al., 2013 [26] (South Korea)

NR

N = 79

• Mean annual hospitalization rate per patient: 0.3

• Mean number of admissions among those who were admitted: 3.08

de la Rosa et al., 2016 [19] (Spain)

2013

N = 456

• Mean annual hospitalization rate per patient: 0.34 ± 0.9

• Mean annual hospitalization rate increased from 0.14 ± 0.5 per patient for patients with mild bronchiectasis to 1.05 ± 1.6 for those with severe bronchiectasis (p < 0.001)

Germino and Liao, 2016 [11] (USA)

2008–2012

N = 5847

• Mean inpatient visits in first year of follow-up: 0.32 per patient

• A total of 22.2, 24.0, and 34.4% of patients with 1, 2, and 3 or more exacerbations had an inpatient visit

McDonnell et al., 2015 [27] (UK)

2007–2009

N = 155

• Mean annual hospitalization rate in 143 patients was 0.9 ± 1.6 per patient with self-reported total number of admissions equal to 131 with 90.8% admissions due to bronchiectasis

Change in hospitalization rates with time

Navaratnam et al., 2014 [16]

2004–2011

NS

• 8611 and 15,885 hospitalizations for bronchiectasis in 2004 and 2011, respectively (1° diagnosis)

• Overall annual increase in hospitalizations of 9% (RR 1.09; 95% CI, 1.08–1.10, p < 0.0001)

Navaratnam et al., 2015 [15]

2009–2013

N = 536

• 74 and 121 admissions to ICU in 2009 and 2013, respectively, equating to a crude annual increase of 8% (RR 1.08; 95% CI, 1.02–1.15, p = 0.01) (1° diagnosis)

Ringshausen et al., 2013 [21]

2005–2011

N = 61,838

• 8.9 and 10.6 hospitalizations per 100,000 in 2005 and 2011, respectively – an average increase of 2.9% (95% CI, 1.7–4.2, p < 0.00001) per year (any diagnosis)

• 1.6 per 100,000 in 2005 to 1.8 per 100,000 in 2011 (from graph) (1° diagnosis)

Sanchez-Munoz et al., 2016 [18] (Spain)

2004–2013

N = 70,676

• 16.5 and 17.0 hospitalizations per 100,000 in 2004 and 2013, respectively (p < 0.001) (1° diagnosis)

Seitz et al., 2010 [13] (USA)

1996–2006

N = 258,947

• Annual percentage change was 2.4% for men and 3.0% for women, demonstrating an increase in the number of hospitalizations over the time period assessed (any diagnosis)

• Increase of 1.7% for men and 2.6% for women (1° diagnosis)

Niewiadomska et al., 2016 [22]

2000–2011

• Crude hospitalization rate increased from 2.0 per 100,000 in 2000 to 8.1 per 100,000 in 2011 (1° diagnosis)

  1. primary, CI confidence interval, ICU intensive care unit, NR not reported, NS not specified, RR relative risk