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Table 1 Demographic and clinical characteristics of the patients

From: Relationship between the respiratory microbiome and the severity of airflow limitation, history of exacerbations and circulating eosinophils in COPD patients

N

All patients

Exacerbations previous year

p

0

1

≥2

72

31

18

23

 

Age, mean (SD)

68 (7.9)

66 (9)

69 (7)

68 (7)

0.387

Sex (male), n (%)

64 (88.9)

27 (87.1)

16 (88.9)

21 (91.3)

0.888

Cumulative smoking (pack-year), median (IQR)

60 (45–80)

60 (44–76)

50 (41–85)

60 (49–97)

0.383

Postbronchodilator FEV1%, median (IQR)

44 (33–60)

52 (42–70)

35 (32–52)

35 (28–49)

0.001

BMI, median (IQR)

27 (24–30)

28 (25–29)

28 (23–30)

26 (23–30)

0.669

Blood eosinophils (× 109/L), median (IQR)

200 (100–270)

200 (130–3009

185 (92–255)

200 (100–300)

0.414

Blood eosinophils (%), median (IQR)

2.4 (1.4–3.4)

2.8 (1.7–3.6)

2 (1.3–2.8)

1.8 (1.1–3.4)

0.156

Blood leucocytes (×109/L), median (IQR)

7845 (6635–9180)

7210 (6520–8940)

7915 (6505–8510)

8110 (7030–10,170)

0.481

Exacerbations last year, median (IQR)

1 (0–2)

0

1

3 (2–4)

 

Airflow limitation severity (GOLD), n (%)

 GOLD 1

6 (8.3)

5 (16.1)

0 (0)

1 (4.3)

0.013

 GOLD 2

19 (26.4)

11 (35.5)

4 (22.2)

4 (17.4)

 GOLD 3

36 (50)

14 (45.2)

12 (66.7)

10 (11.1)

 GOLD 4

11 (15.3)

1 (3.2)

2 (18.2)

8 (34.8)