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Table 1 Demographic and clinical characteristics of the patients

From: Relationship between the respiratory microbiome and the severity of airflow limitation, history of exacerbations and circulating eosinophils in COPD patients

N All patients Exacerbations previous year p
0 1 ≥2
72 31 18 23  
Age, mean (SD) 68 (7.9) 66 (9) 69 (7) 68 (7) 0.387
Sex (male), n (%) 64 (88.9) 27 (87.1) 16 (88.9) 21 (91.3) 0.888
Cumulative smoking (pack-year), median (IQR) 60 (45–80) 60 (44–76) 50 (41–85) 60 (49–97) 0.383
Postbronchodilator FEV1%, median (IQR) 44 (33–60) 52 (42–70) 35 (32–52) 35 (28–49) 0.001
BMI, median (IQR) 27 (24–30) 28 (25–29) 28 (23–30) 26 (23–30) 0.669
Blood eosinophils (× 109/L), median (IQR) 200 (100–270) 200 (130–3009 185 (92–255) 200 (100–300) 0.414
Blood eosinophils (%), median (IQR) 2.4 (1.4–3.4) 2.8 (1.7–3.6) 2 (1.3–2.8) 1.8 (1.1–3.4) 0.156
Blood leucocytes (×109/L), median (IQR) 7845 (6635–9180) 7210 (6520–8940) 7915 (6505–8510) 8110 (7030–10,170) 0.481
Exacerbations last year, median (IQR) 1 (0–2) 0 1 3 (2–4)  
Airflow limitation severity (GOLD), n (%)
 GOLD 1 6 (8.3) 5 (16.1) 0 (0) 1 (4.3) 0.013
 GOLD 2 19 (26.4) 11 (35.5) 4 (22.2) 4 (17.4)
 GOLD 3 36 (50) 14 (45.2) 12 (66.7) 10 (11.1)
 GOLD 4 11 (15.3) 1 (3.2) 2 (18.2) 8 (34.8)
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