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Table 4 Variables analyses for prediction of mortality in the study patients

From: Interstitial pneumonia with autoimmune features show better survival and less exacerbations compared to idiopathic pulmonary fibrosis

 

Univariate

Multivariate

Characteristics

P

HR

95% CI

P

HR

95% CI

Age

< 0.001

1.035

1.018–1.052

0.034

1.022

1.002–1.044

Male/Female

0.011

1.563

1.106–2.210

0.945

0.976

0.493–1.934

Smoking history

0.032

1.463

1.034–2.071

0.110

1.758

0.879–3.513

Positive autoimmune Ab

< 0.001

0.498

0.347–0.714

0.433

0.804

0.467–1.386

First line treatment

0.549

     

 Systemic corticosteroid

 

1

–

   

 Antifibrotics

 

1.417

0.453–4.432

   

Emphysema from HRCT

0.514

1.132

0.780–1.642

   

FVC (%)

< 0.001

0.964

0.954–0.975

< 0.001

0.970

0.955–0.984

DLCO (%)

< 0.001

0.978

0.969–0.988

0.051

0.988

0.976–1.000

ILD exacerbation (yes/no)

0.003

1.654

1.180–2.317

0.001

2.074

1.366–3.148

ILD type

< 0.001

  

0.039

  

 IPF

 

1

  

1

 

 IPAF

0.008

0.470

0.269–0.821

0.047

0.436

0.192–0.990

 CTD-ILD

< 0.001

0.235

0.135–0.410

0.026

0.401

0.179–0.898

  1. Abbreviations: Ab antibody, CTD-ILD connective tissue disease-related interstitial lung disease, DLCO Diffusing capacity of the lungs for carbon monoxide, FVC forced vital capacity, HRCT high-resolution computed tomography scan, ILD interstitial lung disease, IPAF interstitial pneumonia with autoimmune features, IPF idiopathic pulmonary fibrosis
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BMC Pulmonary Medicine

ISSN: 1471-2466

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