Variable | Cutoff | Sens% | Spec% | PPV% | NPV% | Accuracy% | AUC | 95%CI | P |
|---|
Pleural/serum ratio | > 1.4 | 91.7% | 100% | 100% | 96.5% | 97.5% | 0.94 | 0.85–1.0 | < 0.001 (HS) |
Pleural/serum ratio | < 0.9 | 83.3% | 96.4% | 90.9% | 93.1% | 92.5% | 0.90 | 0.77–1.0 | < 0.001 (HS) |
- The cutoff value of pleural/serum IL-33 ratio for the diagnosis of tuberculous pleural effusion was > 1.4. Therefore patients with pleural/serum IL-33 ratio > 1.4 had a high probability of having a tuberculous pleural effusion. The value for the area under the corresponding ROC curve (AUC) was 0.94. The 95% confidence interval was 0.85–1.0; the corresponding sensitivity and specificity were 91.7 and 100% (P < 0.001). The cutoff value of pleural/serum IL-33 ratio for the diagnosis of malignant pleural effusion is < 0.9, therefore patients with pleural/serum IL-33 ratio < 0.9 has a high probability of having a malignant pleural effusion. The value for the area under the corresponding ROC curve (AUC) is 0.90. The 95% confidence interval was 0.77–1.0, the corresponding sensitivity and specificity were 83.3and 96.4% (P < 0.001)
