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Table 4 Overexpression of C/EBPα decreases cells apoptosis and necrosis after exposure to hyperoxia

From: Effects of C/EBPα overexpression on alveolar epithelial type II cell proliferation, apoptosis and surfactant protein-C expression after exposure to hyperoxia

Group

Apoptosis rate

Air (AG)

9.76 ± 0.67

Air+pcDNA3.1(+)-C/EBPα (A + C)

8.97 ± 0.46&

Air+pcDNA3.1(+)-empty (A + E)

9.36 ± 0.39

Hyperoxia (HG)

13.01 ± 0.86*

Hyperoxia+pcDNA3.1(+)-C/EBPα (H + C)

9.51 ± 0.62#

Hyperoxia+pcDNA3.1(+)-empty (H + E)

13.88 ± 0.54*

  1. Apoptosis rate of cells was analyzed by flow cytometry in each group. Values are means ± SD from ten independent experiments (n = 10); *P < 0.05 vs. AG; #P < 0.05 vs. HG or H + E; &P > 0.05 vs. AG or A + E
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BMC Pulmonary Medicine

ISSN: 1471-2466

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