Fig. 3
From: LncRNA PLAC 2 downregulated miR-21 in non-small cell lung cancer and predicted survival
PLAC2 over-expression resulted in miR-21 down-regulation in NSCLC cells. Linear regression was used to analyze the correlation between PLAC2 and miR-21. In NSCLC tissues, PLAC2 and miR-21 were inversely and significantly correlated (a). In non-tumor tissues, PLAC2 and miR-21 were not significantly correlated (b). PLAC2 and miR-21 over-expression was achieved at 24 h after transfection (c). Moreover, PLAC2 over-expression in NSCLC cells resulted in the down-regulation of miR-21 (d). However, miR-21 over-expression did not significantly affect PLAC2 expression (e)