Combined pulmonary fibrosis and emphysema and idiopathic pulmonary fibrosis in non-small cell lung cancer: impact on survival and acute exacerbation

Table 4 Clinical factors associated with all-cause mortality (multivariate analysis)

Variables	HR	95% CI	P value
BMI, kg/m²	0.99	0.95–1.04	0.775
CPFE, yes	0.89	0.66–1.21	0.466
NSCLC Stage ≥ III	3.15	2.21–4.49	< 0.001
ECOG	1.30	1.09–1.55	0.003
GAP Score	1.31	1.16–1.48	< 0.001
Histologic type
Adenocarcinoma	1.00
Squamous cell carcinoma	0.97	0.70–1.34	0.849
Others	1.27	0.80–1.99	0.309

Data are presented as hazard ratios (95% confidence intervals)
Definition of abbreviations: BMI Body Mass Index, CPFE Combined Pulmonary Fibrosis and Emphysema, NSCLC Non-Small Cell Lung Cancer, ECOG Eastern Cooperative Oncology Group performance status, GAP Score Gender–Age–Physiology Score

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