Table 1 Distribution of EGFR mutations according to patients’ characteristics
Characteristics | Number of patients (%) | EGFR mutated cases | ||
|---|---|---|---|---|
No. | % | p | ||
Total cases analyzed | 1440 | 181 | 12.6 | Â |
Sex | ||||
 Males | 963 (67) | 66 | 6.9 | < 0.001 |
 Females | 477 (33) | 115 | 24.1 | |
Age at diagnosis | ||||
 Median (range) | 67 (30–88) | |||
 ≤ 50 years | 112 (8) | 20 | 17.9 | 0.107* |
 51–60 years | 264 (18) | 31 | 11.7 | |
 61–70 years | 544 (38) | 56 | 10.3 | |
 > 70 years | 520 (36) | 74 | 14.2 | |
Smoking habitus | ||||
 Smoker | 475 (33) | 17 | 3.6 | < 0.001** |
 Former smoker | 538 (37) | 45 | 8.4 | |
 Never smoker | 186 (13) | 109 | 58.6 | |
 Unknown | 241 (17) | 10 | 4.1 |  |
Type of sample | ||||
 Primary tumor | 1243 (86) | 156 | 12.6 | 0.952 |
 Metastasis | 197 (14) | 25 | 12.7 | |
Sample’s origin | ||||
 Biopsy | 1198 (83) | 149 | 12.4 | 0.818 |
 Surgery | 242 (17) | 32 | 13.2 | |