Table 3 Distribution of ALK rearrangements according to patients’ characteristics
Characteristics | Number of patients (%) | ALK mutated cases | ||
|---|---|---|---|---|
No. | % | p | ||
Total cases analyzed | 899 | 48 | 5.3 | Â |
Sex | ||||
 Males | 641 (67) | 27 | 4.2 | < 0.001 |
 Females | 258 (33) | 21 | 8.1 | |
Age at diagnosis | ||||
 ≤ 50 years | 62 (8) | 8 | 12.9 | 0.014* |
 51–60 years | 168 (18) | 13 | 7.7 | |
 61–70 years | 344 (38) | 15 | 4.4 | |
 > 70 years | 325 (36) | 12 | 3.7 | |
Smoking habitus | ||||
 Smoker | 288 (33) | 11 | 3.8 | 0.459** |
 Former smoker | 332 (37) | 21 | 6.3 | |
 Never smoker | 107 (13) | 8 | 7.5 | |
 Unknown | 172 (17) | 8 | 4.7 |  |
Type of sample | ||||
 Primary tumor | 783 (87) | 41 | 5.2 | 0.892 |
 Metastasis | 116 (13) | 7 | 6.0 | |
Sample’s origin | ||||
 Biopsy | 730 (83) | 39 | 5.3 | 0.850 |
 Surgery | 169 (17) | 9 | 5.6 | |