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Table 4 Distribution of cMET rearrangements according to patients’ characteristics

From: EGFR, KRAS, BRAF, ALK, and cMET genetic alterations in 1440 Sardinian patients with lung adenocarcinoma

Characteristics

Number of patients (%)

cMET mutated cases

No.

%

p

Total analyzed

778

16

2.1

 

Sex

 Males

641 (69)

9

1.4

0.231

 Females

242 (31)

7

2.9

Age at diagnosis

 ≤ 50 years

55 (7)

1

1.8

1.000*

 51–60 years

139 (18)

5

2.6

 61–70 years

301 (39)

5

1.7

 > 70 years

283 (36)

5

1.8

Smoking habitus

 Smoker

264 (33)

5

1.9

1.000**

 Former smoker

295 (37)

6

2.0

 Never smoker

94 (13)

2

2.1

 Unknown

125 (17)

3

2.4

 

Type of sample

 Primary tumor

661 (85)

13

2.0

0.720

 Metastasis

117 (15)

3

2.6

Sample’s origin

 Biopsy

654 (84)

13

2.0

0.730

 Surgery

124 (16)

3

2.4

  1. * Patients ≤ 50 years vs patients ≥ 50 years; ** Never smokers vs smokers and ex-smokers; significance at 0.05