High positive end expiratory pressure levels affect hemodynamics in elderly patients with hypertension admitted to the intensive care unit: a prospective cohort study

Zhou, Lili; Cai, Guoen; Xu, Zhihui; Weng, Qinyong; Ye, Qinyong; Chen, Cunrong

doi:10.1186/s12890-019-0965-9

Table 2 Effect of different PEEP levels on hemodynamics. Data are shown as mean ± SD

From: High positive end expiratory pressure levels affect hemodynamics in elderly patients with hypertension admitted to the intensive care unit: a prospective cohort study

		PEEP(cmH₂O)
		0	2	4	6	8	10	12
SBP (mmHg)	0	119.1 ± 9.9	120.2 ± 8.4	119.9 ± 9.2	121.3 ± 6.6	121.9 ± 9.4	120.8 ± 9.2	122.6 ± 9.1
SBP (mmHg)	1	151.6 ± 13.2	152.6 ± 9.4	154.2 ± 10.0	146.1 ± 14.2	142.8 ± 14.4	139.8 ± 15.3^bc	137.1 ± 14.1^abc
DBP (mmHg)	0	67.4 ± 5.3	68.6 ± 6.7	67.9 ± 5.7	69.6 ± 6.2	70.5 ± 6.9	69.7 ± 7.5	69.6 ± 8.7
DBP (mmHg)	1	82.0 ± 12.0	84.1 ± 11.4	82.5 ± 12.9	77.4 ± 13.1	76.0 ± 12.4	73.3 ± 13.8	72.2 ± 11.7^b
MABP (mmHg)	0	84.7 ± 3.7	85.7 ± 4.3	85.6 ± 4.3	86.8 ± 4.9	87.6 ± 4.9	86.7 ± 4.6	87.1 ± 5.4
MABP (mmHg)	1	105.1 ± 10.1	107.6 ± 7.9	106.0 ± 9.7	100.2 ± 10.9	98.1 ± 10.4^b	95.3 ± 11.5^bc	93.8 ± 10.0^abc
CVP (mmHg)	0	7.2 ± 1.2	7.4 ± 1.2	7.6 ± 1.2	7.8 ± 1.3	8.0 ± 1.2	8.2 ± 1.3	8.4 ± 1.3
CVP (mmHg)	1	8.1 ± 3.3	8.4 ± 3.1	9.0 ± 4.2	8.7 ± 2.6	9.0 ± 2.9	9.1 ± 2.8	9.3 ± 2.9
ScvO₂ (%)	0	68.4 ± 7.3	68.6 ± 5.8	69.3 ± 6.0	69.9 ± 7.4	71.3 ± 5.7	70.4 ± 8.0	72.0 ± 6.6
ScvO₂ (%)	1	67.3 ± 8.5	69.3 ± 8.9	70.8 ± 7.6	67.8 ± 5.7	65.3 ± 6.4	64.0 ± 5.7^c	61.9 ± 6.2^cd
HR (bpm)	0	82.6 ± 12.5	82.9 ± 12.7	83.3 ± 12.9	83.8 ± 13.5	82.1 ± 13.2	82.6 ± 13.3	82.7 ± 12.8
HR (bpm)	1	80.2 ± 12.5	78.5 ± 12.2	76.9 ± 10.4	80.9 ± 12.7	82.7 ± 10.7	85.1 ± 9.8	88.2 ± 11.5^c
Ppeak (cmH₂O)	0	20.4 ± 4.9	21.5 ± 4.6	22.3 ± 4.4	23.6 ± 4.5	24.6 ± 4.4	25.7 ± 4.5^a	27.3 ± 4.8^ab
Ppeak (cmH₂O)	1	20.8 ± 4.1	21.8 ± 4.3	23.3 ± 4.6	24.6 ± 5.1	26.1 ± 4.9^a	27.4 ± 4.8^ab	29.3 ± 4.7^abc
Pmean (cmH₂O)	0	10.1 ± 2.1	11.1 ± 2.2	11.9 ± 2.3	13.1 ± 2.5^a	13.9 ± 2.2^ab	15.1 ± 2.4^abc	16.2 ± 2.7^abcd
Pmean (cmH₂O)	1	10.3 ± 2.3	11.2 ± 2.0	12.3 ± 2.1	13.7 ± 2.2^ab	14.7 ± 2.1^abc	16.0 ± 2.2^abcd	17.5 ± 2.2^abcde
VT (ml)	0	644.6 ± 95.3	649.7 ± 96.8	654.0 ± 96.1	651.9 ± 94.3	642.6 ± 106.2	646.3 ± 106.4	645.3 ± 107.2
VT (ml)	1	584.0 ± 119.1	587.0 ± 118.3	591.1 ± 114.1	589.6 ± 115.4	586.9 ± 117.7	587.4 ± 116.3	585.3 ± 117.3
MV (L/min)	0	11.7 ± 1.6	11.7 ± 1.6	11.8 ± 1.6	11.8 ± 1.5	11.6 ± 1.8	11.7 ± 1.8	11.7 ± 1.9
MV (L/min)	1	10.5 ± 2.1	10.6 ± 2.1	10.8 ± 2.0	10.7 ± 2.0	10.8 ± 2.1	10.9 ± 2.0	10.7 ± 2.0
SpO₂	0	100.0 ± 0.0	100.0 ± 0.0	100.0 ± 0.0	100.0 ± 0.0	100.0 ± 0.0	100.0 ± 0.0	100.0 ± 0.0
(%)	1	99.9 ± 0.5	99.9 ± 0.3	100.0 ± 0.2	100.0 ± 0.2	100.0 ± 0.2	100.0 ± 0.2	99.9 ± 0.5

SBP Systolic blood pressure, DBP Diastolic blood pressure, MABP Mean arterial blood pressure, CVP Central venous pressure, ScvO₂ Central venous oxygen saturation, HR Heart rate, Ppeak Peak airway pressure, Pmean Mean airway pressure, VT Tidal volume, MV Minute ventilation volume, SpO₂ Peripheral oxygen saturation; 0: Control group; 1: Hypertension group;
^aP < 0.05, compared with PEEP 2 cm H₂O: ^bP < 0.05, compared with PEEP 4 cm H₂O: ^cP < 0.05, compared with PEEP 6 cm H₂O: ^dP < 0.05, compared with PEEP 8 cm H₂O: ^eP < 0.05. In the same group of blood pressure, compared with PEEP 0 cm H₂O: ^aP < 0.05, compared with PEEP 2 cm H₂O: ^bP < 0.05, compared with PEEP 4 cm H₂O: ^cP < 0.05, compared with PEEP 6 cm H₂O: ^dP < 0.05, compared with PEEP 8 cm H₂O: ^eP < 0.05

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