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Table 2 miRNA differentially expressed in the serum of women in the COPD-BS, COPD-TS (GOLD stages I–II), H-BS and C groups

From: miR-34a in serum is involved in mild-to-moderate COPD in women exposed to biomass smoke

Compared groups

microRNA

Regulation

level

Fold change

P-value

COPD-BS vs. COPD-TS

hsa-miR-34a-5p

down-regulated

−8.77

0.020460

COPD-BS vs. C

hsa-miR-374a-5p

down-regulated

−12.29

0.000291

COPD-BS vs. H-BS

hsa-miR-150-5p

up-regulated

20.66

0.000064

hsa-miR-191-5p

up-regulated

24.95

0.004144

hsa-miR-223-3p

up-regulated

30.19

0.000645

COPD-TS vs. C

hsa-miR-21-5p

down-regulated

−17.89

0.007987

  1. Data are expressed as the regulation, fold change and P-value
  2. Abbreviations: C control healthy women, COPD-BS COPD by biomass smoke exposure, COPD-TS COPD by tobacco smoke, H-BS women exposed to BS without COPD