Fig. 1
From: Prognostic value of cardiopulmonary exercise testing in patients with systemic sclerosis
Survival of patients after first diagnosis of SSc (Kaplan–Meier analyses). a Overall. b According to limited or disseminated disease. Bold line: group 1 (dcSSc, n=88); dashed line: group 2 (n=122) comprising lcSSc (n=71) and CREST-syndrome (n=51). c Divided by 6-MWD, Youden index defining best cut-off at 413 m. d Divided by pulmonary hypertension. Bold line: PAPmean ≥25mmHg, dashed line: PAPmean <25mmHg. 6-MWD: 6 minute walking distance; CREST: Calcinosis, Raynaud´s syndrome, Oesophageal dysmotility, Sclerodactyly, Telangiectasia; dcSSc: disseminated cutaneous manifestation; lcSSc: limited cutaneous manifestation; PAPmean: mean pulmonary arterial pressure