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Table 2 Comparison of PFT in HDLI survivors vs. control subjects

From: Early-life exposure to humidifier disinfectant determines the prognosis of lung function in children

 

HDLI survivors

Control group

P-value

n

mean (SE)

n

mean (SE)

A. Boy, Over 7 years

 FVC (% of pred)

47

87.4 (2.2)

75

98.5 (1.2)

< 0.001

 FEV1 (% of pred)

47

86.0 (2.0)

75

96.7 (1.3)

< 0.001

 FEV1/FVC

47

89.1 (0.7)

75

89.0 (0.5)

0.907

 cor. DLco (% of pred)

47

74.0 (2.4)

81

87.1 (1.3)

< 0.001

Girl, above 7 years

 FVC (% of pred)

34

84.4 (2.2)

39

94.1 (1.4)

< 0.001

 FEV1 (% of pred)

34

82.4 (2.4)

39

93.5 (1.5)

< 0.001

 FEV1/FVC

34

90.4 (1.1)

39

91.8 (0.6)

0.256

 cor. DLco (% of pred)

34

68.3 (1.9)

41

78.2 (1.8)

< 0.001

B. Boy, above 8 years

 FVC (% of pred)

23

83.1 (3.4)

52

98.5 (1.5)

< 0.001

 FEV1 (% of pred)

23

81.7 (3.1)

52

95.9 (1.6)

< 0.001

 FEV1/FVC

23

89.7 (1.0)

52

88.6 (0.6)

0.308

 cor. DLco (% of pred)

28

74.4 (3.5)

55

89.3 (1.5)

< 0.001

Girl, above 8 years

 FVC (% of pred)

15

80.9 (2.3)

27

92.1 (1.5)

< 0.001

 FEV1 (% of pred)

15

77.3 (2.7)

27

90.4 (1.4)

< 0.001

 FEV1/FVC

15

89.8 (2.2)

27

91.5 (0.8)

0.465

 cor. DLco (% of pred)

19

67.9 (2.0)

29

80.8 (2.3)

< 0.001

C. Boy, above 9 years

 FVC (% of pred)

18

81.0 (3.6)

31

98.1 (1.8)

< 0.001

 FEV1 (% of pred)

18

79.3 (3.0)

31

95.1 (1.9)

< 0.001

 FEV1/FVC

18

89.7 (1.1)

31

88.5 (0.7)

0.390

 cor. DLco (% of pred)

25

74.1 (3.4)

32

89.6 (2.3)

< 0.001

Girl, above 9 years

 FVC (% of pred)

13

80.8 (2.6)

15

90.5 (1.7)

0.004

 FEV1 (% of pred)

13

76.6 (3.0)

15

87.7 (1.4)

0.004

 FEV1/FVC

13

89.2 (2.5)

15

91.3 (1.1)

0.462

 cor. DLco (% of pred)

15

68.3 (2.1)

15

83.7 (2.6)

< 0.001

  1. P values for the comparison between HDLI survivors and controls calculated with the Student t test. HDLI, HD associated lung injury; N, number; SE, standard errors of the estimated mean; pred, predicted; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 sec; FEV1/FVC, the ratio of forced expiratory volume in 1 sec to forced vital capacity; FEF25–75: forced expiratory flow between 25 and 75% of vital capacity; DLco, diffusing capacity of the lung for carbon monoxide; cor. DLco, corrected DLco