Table 3 Comparison of exposure characteristics based on lung function phenotype in HDLI survivors
From: Early-life exposure to humidifier disinfectant determines the prognosis of lung function in children
| Â | FVC | Corrected DLco | ||||
|---|---|---|---|---|---|---|
|  | Persistently low (n = 12) | Normal (n = 27) | p-value | Persistently low (n = 24) | Normal (n = 4) | p-value |
HD type (%) | ||||||
 PHMG, only use | 50.0 | 51.9 | 0.787 | 50.0 | 25.0 | 0.353 |
 PGH, only use | 0.0 | 3.7 |  | 0 | 0 |  |
 CMIT/MIT, only use | 0.0 | 3.7 |  | 0 | 0 |  |
 Mixed | 50.0 | 40.7 |  | 50.0 | 75.0 |  |
aHD exposure intensity/weight at exposure (%) | ||||||
 1st quartile | 16.7 | 33.3 | 0.749 | 29.2 | 25.0 | 0.564 |
 2nd quartile | 33.3 | 25.9 |  | 20.8 | 50.0 |  |
 3rd quartile | 33.3 | 29.6 |  | 29.2 | 25.0 |  |
 4th quartile | 16.7 | 11.1 |  | 20.8 | 0.0 |  |
aHD exposure intensity during sleep/weight at exposure (%) | ||||||
 1st quartile | 25.0 | 29.6 | 0.509 | 33.3 | 25.0 | 0.037 |
 2nd quartile | 25.0 | 33.3 |  | 12.5 | 75.0 |  |
 3rd quartile | 25.0 | 29.6 |  | 33.3 | 0.0 |  |
 4th quartile | 25.0 | 7.4 |  | 20.8 | 0.0 |  |
Age on initial exposure (%) | ||||||
 < 12.0 months | 83.3 | 37.0 | 0.008 | 62.5 | 0.0 | 0.020 |
 ≥ 12.0 months | 16.7 | 63.0 |  | 37.5 | 100.0 |  |
Fetal exposure (%) | 16.7 | 3.7 | 0.161 | 8.3 | 0.0 | 0.549 |
Total duration of use (month) | 13.7 | 15.9 | 0.690 | 15.7 | 22.9 | 0.466 |
Distance between bed and HD (%) | ||||||
 < 1.0 m | 50.0 | 44.5 | 0.748 | 54.2 | 0.0 | 0.044 |
 ≥ 1.0 m | 50.0 | 55.6 |  | 45.8 | 100.0 |  |
Direction dispersed into room (%) | ||||||
 Diagonal | 41.7 | 44.4 | 0.736 | 37.5 | 25.0 | 0.459 |
 Forward | 33.3 | 40.7 |  | 41.7 | 25.0 |  |
 Unknown | 25.0 | 14.8 |  | 20.8 | 50.0 |  |
Use of HD during sleep (%) | 91.7 | 100.0 | 0.129 | 95.8 | 100.0 | 0.678 |