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Table 1 Basic characteristics of patients with PVOD

From: Targeted therapy in pulmonary veno-occlusive disease: time for a rethink?

Patient number12345
SexMFMMM
Age ranges (year)35–4035–4030–3532–3725–30
BMI (kg/m2)18.018.721.922.415.5
Chest tightness / Shortness of breathYesYesYesYesYes
Edema of lower extremitiesNoNoYesNoNo
HRCT
 Interlobular septal thickeningYesYesNoYesYes
 Ground glass opacitiesYesYesYesYesYes
 Enlarged mediastinal lymph nodesNoNoYesNoNo
EIF2AK4 mutationc.2488C > T; c.989_990delc.2965C > T; c.4724 T > Cc.1948C > Tc.3460A > T; c.4736 T > Cc.4414_4417del
Medical history
 SmokingYesNoNoYesYes
 DrinkingNoNoNoYesNo
 Acute coronary diseaseNoNoNoNoNo
 HypertensionNoNoNoNoNo
 HyperlipemiaNoNoNoNoNo
 DiabetesNoNoNoNoNo
 Obstructive sleep apneaNoNoNoNoNo
Time from onset to admission (month)72184606
  1. BMI Body mass index, HRCT High resolution computed tomography, EIF2AK4 Eukaryotic translation initiation factor 2 alpha kinase 4