Table 1 Basic characteristics of patients with PVOD
From: Targeted therapy in pulmonary veno-occlusive disease: time for a rethink?
Patient number | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|
Sex | M | F | M | M | M |
Age ranges (year) | 35–40 | 35–40 | 30–35 | 32–37 | 25–30 |
BMI (kg/m2) | 18.0 | 18.7 | 21.9 | 22.4 | 15.5 |
Chest tightness / Shortness of breath | Yes | Yes | Yes | Yes | Yes |
Edema of lower extremities | No | No | Yes | No | No |
HRCT | |||||
Interlobular septal thickening | Yes | Yes | No | Yes | Yes |
Ground glass opacities | Yes | Yes | Yes | Yes | Yes |
Enlarged mediastinal lymph nodes | No | No | Yes | No | No |
EIF2AK4 mutation | c.2488C > T; c.989_990del | c.2965C > T; c.4724 T > C | c.1948C > T | c.3460A > T; c.4736 T > C | c.4414_4417del |
Medical history | |||||
Smoking | Yes | No | No | Yes | Yes |
Drinking | No | No | No | Yes | No |
Acute coronary disease | No | No | No | No | No |
Hypertension | No | No | No | No | No |
Hyperlipemia | No | No | No | No | No |
Diabetes | No | No | No | No | No |
Obstructive sleep apnea | No | No | No | No | No |
Time from onset to admission (month) | 72 | 1 | 84 | 60 | 6 |