Fig. 1

Radial probe endobronchial ultrasound (RP-EBUS) guided transbronchial lung cryobiopsy (TBLC) for acute respiratory distress syndrome (ARDS). a RP-EBUS screening of the target biopsy position. b Marking the biopsy distance on the cryoprobe compared to that on RP-EBUS. c1 Prophylactic placement of the bronchial blocker and insertion of the cryoprobe into the target segment. c2 Combined guidance with cone beam CT after placing the cryoprobe in patient 5. d Transbronchial lung cryobiopsy was performed after freezing for 4 s. e The bronchial blocker was filled to stop the bleeding. f Bronchial blockers were continuously placed in target bronchi for patients with massive bleeding