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Table 1 Characteristics of the overall population

From: Procalcitonin and C-reactive protein perform better than the neutrophil/lymphocyte count ratio in evaluating hospital acquired pneumonia

 

Non-infection n = 254

HAP n = 339

Age (years)

66.6 ± 17.1

71.0 ± 17.9 **

Sex (M / F)

152 / 102

252 / 87 *

WBC abnormalities, n, (%)

54 (21.3%)

130 (38.2%) *

NE abnormalities, n, (%)

183 (72.0%)

254 (74.7%) *

APACHE II score (mean ± sd)

17.7 ± 5.9

21.7 ± 6.1 ***

NLCR

10.2 ± 9.8

13.0 ± 17.1 *

PCT (ng/ml)

0.75 ± 3.25

4.60 ± 15.97 ***

CRP (mg/ml)

45.8 ± 50.6

73.3 ± 79.6 ***

Blood lactate (mmol/l)

1.6 ± 1.3

1.5 ± 0.8

Surgery, n, (%)

100 (39.4%)

87 (25.6%) **

28 days survival, n, (%)

205 (80.7%)

233 (68.5%) **

Diabetes mellitus, n, (%)

5 (2.0%)

0 (0) *

Cardiovascular disease, n, (%)

28 (11.0%)

18 (5.3%) *

Hypertension, n, (%)

5 (2.0%)

1 (0.3%) *

Malignancies, n, (%)

54 (21.3%)

10 (2.9%) ***

COPD, n, (%)

10 (3.9%)

17 (5.0%)

Liver cirrhosis, n, (%)

2 (0.8%)

0 (0)

Renal failure, n, (%)

2 (0.8%)

16 (4.7%) **

  1. Data were expressed as Mean ± standard deviation or number (percentage) of current group. *p < 0.05, **p < 0.01, ***p < 0.001 vs non-infection group. WBC white blood count; NE neutrophil; NLCR neutrophil/lymphocyte count ratio; PCT procalcitonin; CRP C-reactive protein; HAP hospital acquired pneumonia; COPD chronic obstructive pulmonary disease