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Table 5 Baseline characteristics according to allergy status

From: Real-life experience with benralizumab during 6 months

Variables

Non-atopic

(n = 28)

Atopic

(n = 14)

p

Age, years; md (IR)

56 (20)

49.5 (15)

0.153

Women, n (%)

23 (82)

10 (71)

0.451

BMI, md (IR)

28.5 (7.5)

25 (10)

0.131

Age at diagnosis, years; md (IR)

26.5 (23)

24.5 (16)

0.913

Corticosteroid-dependent, n (%)

13 (46)

4 (28)

0.331

Nasal polyps, n (%)

5 (18)

7 (50)

0.067

AERD, n (%)

3 (11)

3 (21)

0.383

ACT, md (IR)

13 (6)

15 (6)

0.730

ED visits in the previous year; md (IR)

5 (3)

3 (3)

0.062

Cycles of OCS in the previous year; md (IR)

7 (3)

4.5 (4)

0.062

Oral prednisone (or equivalent) dose, mg/day; md (IR)

20 (15)

15 (23)

0.412

Post-BD FEV1, mL; md (IR)

1520 (910)

1425 (545)

0.947

Post-BD FEV1, %; md (IR)

65 (13)

69.5 (12)

0.117

FeNO, ppb; md (IR)

68.5 (32.5)

44.5 (45)

0.098

Blood eosinophil count, cells/ÎĽL; md (IR)

713 (297)

695 (235)

0.743

IgE, IU/mL; md (IR)

53 (106)

215 (175)

< 0.001

  1. Abbreviations: ACT Asthma Control Test, AERD Aspirin-exacerbated respiratory disease, BD Bronchodilator, BMI Body mass index, ED Emergency department, FeNO Fractional exhaled nitric oxide, FEV1 Forced expiratory volume in 1 s, IR Interquartile range, md Median, ppb Parts per billion, OCS Oral corticosteroids