Fig. 7

Mitigated NIK/NF-kappaB signaling and IL-17 signaling pathways in MSC transplanted samples. Protein samples were analyzed by Western blotting against antibodies of RTKN2, total and phosphorylation of IκBα, phosphorylation of NF-kappaB, Caspase3, Caspase9, CyclinD1 and β-actin. Protein samples were extracted from lungs of different experimental groups treated with PQ (Con: Control group; PQ: paraquat-treated group; P + M: PQ treatment with MSC transplantation group) at different time points, 12 h, 24 h and 48 h