From: Do-not-resuscitate orders in patients with community-acquired pneumonia: a retrospective study
No DNR order n = 1140 | DNR order n = 177 | P-value | |
---|---|---|---|
Age, median (IQR) | 70 (55–80) | 82 (73–88) | < 0.001 |
Sex, male | 47% (539) | 48% (85) | 0.85 |
Nursing home | 6% (73) | 41% (72) | < 0.001 |
Comorbidities | |||
COPD | 18% (200) | 24% (42) | 0.045 |
Oher chronic pulmonary disease | 13% (143) | 6% (11) | 0.014 |
Malignancy | 9% (101) | 10% (18) | 0.57 |
Chronic heart disease | 20% (223) | 32% (57) | < 0.001 |
Chronic neurological disease | 12% (132) | 29% (51) | < 0.001 |
Diabetes | 13% (144) | 10% (17) | 0.25 |
Chronic liver disease | 1% (9) | 2% (3) | 0.24 |
Chronic kidney disease | 3% (37) | 2% (4) | 0.48 |
Number of comorbidities | |||
None | 41% (468) | 27% (48) | 0.001 |
One | 35% (395) | 41% (71) | 0.45 |
More than one | 24% (267) | 32% (56) | 0.05 |
Severity | |||
CURB-65 0–1 | 59% (582) | 15% (22) | < 0.001 |
CURB-65 2 | 28% (281) | 34% (49) | 0.43 |
CURB-65 3–5 | 13% (129) | 50% (72) | < 0.001 |
ICU | 7% (79) | 27% (47) | < 0.001 |
Intubation | 3% (35) | 12% (22) | < 0.001 |
Antibiotic treatmenta | |||
Monotherapy penicillinb | 47% (535) | 31% (54) | < 0.001 |
Monotherapy other beta-lactam | 29% (332) | 36% (63) | 0.08 |
Combination therapy | 14% (163) | 24% (43) | 0.001 |
Other | 10% (110) | 10% (17) | 0.99 |
Mortality | |||
30-day | 4% (40) | 62% (109) | < 0.001 |
90-day | 6% (69) | 75% (133) | < 0.001 |
180-day | 9% (102) | 81% (143) | < 0.001 |