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Table 2 Association between serum OPN levels and clinicopathological characteristics in SCLC patients

From: Prognostic significance of serum osteopontin levels in small cell lung cancer

Characteristics

Number

OPN level (ng/ml)

P

Age, yr

  

0.954

  ≥ 60

54

73.78 ± 16.55

 

  < 60

42

73.43 ± 17.90

 

Gender

  

0.317

 Male

66

75.38 ± 16.44

 

 Female

30

68.38 ± 18.19

 

Smoking history

  

0.077

 Ever smoker

58

68.32 ± 20.11

 

 Never smoker

38

78.94 ± 11.13

 

Performance status

  

0.174

 0–1

56

70.02 ± 17.39

 

 2–3

40

78.27 ± 15.55

 

Disease stage

  

0.012

 Limited

28

66.32 ± 19.64

 

 Extended

58

80.94 ± 9.41

 

Tumor size (cm)

  

0.034

  ≥ 3

76

77.96 ± 14.31

 

  < 3

20

60.63 ± 18.18

 

Lymph node metastasis

  

0.037

 N0

26

64.08 ± 21.85

 

 N1–3

70

79.40 ± 9.72

 

Responses

  

0.485

 CR + PR

78

71.15 ± 18.33

 

 SD + PD

18

78.01 ± 13.74

 
  1. OPN, osteopontin; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease