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Table 2 Association between serum OPN levels and clinicopathological characteristics in SCLC patients

From: Prognostic significance of serum osteopontin levels in small cell lung cancer

Characteristics Number OPN level (ng/ml) P
Age, yr    0.954
  ≥ 60 54 73.78 ± 16.55  
  < 60 42 73.43 ± 17.90  
Gender    0.317
 Male 66 75.38 ± 16.44  
 Female 30 68.38 ± 18.19  
Smoking history    0.077
 Ever smoker 58 68.32 ± 20.11  
 Never smoker 38 78.94 ± 11.13  
Performance status    0.174
 0–1 56 70.02 ± 17.39  
 2–3 40 78.27 ± 15.55  
Disease stage    0.012
 Limited 28 66.32 ± 19.64  
 Extended 58 80.94 ± 9.41  
Tumor size (cm)    0.034
  ≥ 3 76 77.96 ± 14.31  
  < 3 20 60.63 ± 18.18  
Lymph node metastasis    0.037
 N0 26 64.08 ± 21.85  
 N1–3 70 79.40 ± 9.72  
Responses    0.485
 CR + PR 78 71.15 ± 18.33  
 SD + PD 18 78.01 ± 13.74  
  1. OPN, osteopontin; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease