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Table 1 Pathological evaluation of core biopsy samples

From: Spontaneous regression of ALK fusion protein-positive non-small cell lung carcinoma: a case report and review of the literature

Histological Analysis Molecular Analysis
TTF-1 Weak focal positivity EGFR PCR Insufficient DNA
Nap A Weak focal positivity ALK fusion protein IHC Detected
CK 7 Positive ALK rearrangement ISH Detected
CK 20 Positive PD-L1 IHC Not detected
CA 19–9 Positive  
CDX-2 Negative
  1. (TTF-1 = thyroid transcription factor 1; Nap A = napsin A; CK 7 = cytokeratin-7; CK 20 = cytokeratin-20; CA 19.9 = carbohydrate antigen 19–9; CDX2 = caudal type homeobox 2; PCR = polymerase chain reaction; IHC = immunohistochemistry; ISH = in situ hybridisation; PD-L1 = programmed death ligand 1)