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Table 1 Pathological evaluation of core biopsy samples

From: Spontaneous regression of ALK fusion protein-positive non-small cell lung carcinoma: a case report and review of the literature

Histological Analysis

Molecular Analysis

TTF-1

Weak focal positivity

EGFR PCR

Insufficient DNA

Nap A

Weak focal positivity

ALK fusion protein IHC

Detected

CK 7

Positive

ALK rearrangement ISH

Detected

CK 20

Positive

PD-L1 IHC

Not detected

CA 19–9

Positive

 

CDX-2

Negative

  1. (TTF-1 = thyroid transcription factor 1; Nap A = napsin A; CK 7 = cytokeratin-7; CK 20 = cytokeratin-20; CA 19.9 = carbohydrate antigen 19–9; CDX2 = caudal type homeobox 2; PCR = polymerase chain reaction; IHC = immunohistochemistry; ISH = in situ hybridisation; PD-L1 = programmed death ligand 1)
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BMC Pulmonary Medicine

ISSN: 1471-2466

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