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Table 3 Univariate and multivariate analysis of risk factor for lung cancer recurrence after lobectomy

From: Regional emphysema score is associated with tumor location and poor prognosis in completely resected NSCLC patients

Variable

Univariate

Multivariate

HR (95% CI)

P value

HR (95% CI)

P value

Smoking

1.573 (1.009–2.452)

0.045

1.136 (0.711–1.817)

0.594

Pathologic stage (I)

 II

2.114 (1.294–3.453)

0.003

  

 III

3.408 (2.123–5.468)

< 0.001

2.233 (1.284–3.884)

0.004

Poor differentiation

3.221 (2.065–5.020)

< 0.001

1.980 (1.223–3.206)

0.005

Pleural invasion

2.313 (1.562–3.452)

< 0.001

1.427 (0.925–2.202)

0.108

Lymphatic invasion

2.653 (1.786–3.94)

< 0.001

1.333 (0.801–2.216)

0.269

Vascular invasion

2.600 (1.665–4.060)

< 0.001

1.448 (0.867–2.417)

0.157

High emphysema score (≥3)

1.514 (0.999–2.295)

0.051

  

Higher RES in a lobe with cancer

1.698 (1.139–2.530)

0.009

1.563 (1.011–2.416)

0.044

  1. Abbreviations: HR hazard ratio, CI confidence interval, RES regional emphysema score