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Table 3 Risk factors for hemoptysis

From: Safety of bronchoscopy in patients with malignant hematologic disorders

Characteristic

Patients with hemoptysis (n = 35)

Patients without hemoptysis (n = 281)

p value of univariate analysis

p value in multivariate analysis

Hazard ratio (95% CI)

Age ≤ 70 years

3

36

0.60

  

Sex (male/female)

29/6

206/75

0.22

  

AML and MPAL

17

145

0.74

  

Platelet count (≤20 × 103/μl)

1

28

0.23

0.69

 

Platelet transfusion

17

117

0.43

  

Neutrophil count (≤500)

9

54

0.36

  

Within 180 days from BMT except PBSCT

4

57

0.21

  

Inhalation of oxygen (≥5 L/min)

0

6

1.00

  

Bronchial wash

15

164

0.26

  

BAL

10

79

0.59

  

TBLB

28

93

0.00

0.00

10.40 (4.18–25.90)

Use of midazolam

22

213

0.10

0.01

0.31 (0.14–0.73)

Use of pethidine

32

259

0.75

  

Use of atropine sulfate

30

231

0.61

  
  1. Bold indicates statistical significance
  2. AML Acute myeloid leukemia, BAL Bronchoalveolar lavage, BMT Bone marrow transplantation;
  3. MPAL Mixed phonotype acute leukemia, PBST Peripheral blood stem cell transplantation, TBLB Transbronchial lung biopsy