Table 1 Clinical characteristics of COPD subjects separated according to gender or hypoxaemia status. Median _{[25th – 75th percentiles]}. * p < 0.05; **p < 0,001; Rank-Sum test

Non-hypoxemic

(n = 46)

Hypoxemic

(n = 54)

P value

Age (year)

68 _[65–76]

71,5 _[64–77]

0,745

BMI (kg/m²)

24,3 _{[20,2 – 30,5]}

25,8 _{[22,4 – 30,1]}

0,531

PaO₂ (mmHg)

62 _[59–66]

47 _[41–51]

< 0,001**

PaCO₂ (mmHg)

41 _[37–44]

45,5 _[39–53]

0,002*

pH

7,42 _{[7,40 – 7,45]}

7,42 _{[7,38 – 7,44]}

0,535

FEV₁ (%pv)

34,5 _[29–_46]

31 _[25–44]

0,186

FEV₁/FVC

46,8 _[38–58]

46,3 _[39,5–52]

0,445

TL_CO (%pv)

39,5 _{[32,5 – 49,5]}

29,5 _[23–42,8]

0,002*

TLC (% pv)

91 _[79–104,8]

97,5 _[82–109,8]

0,225

RV (%pv)

143 _{[117,5–171]}

152, 65 _{[114–202,5]}

0,334

Ad_pl level (ng/ml)

11,599,1 _{[6021,6 – 15,073,0]}

9804,7 _{[5857,8 – 13,306,2]}

0,483

Men

(n = 61)

Women

(n = 39)

Age (year)

72 _{[66,7 – 77,2]}

67 _[60–74,7]

0,061

BMI (kg/m²)

25,6 _{[22,4 – 30,5]}

24,8 _{[20,3 – 30,6]}

0,799

PaO₂ (mmHg)

54 _[45–60,5]

55 _[47–61,7]

0,538

PaCO₂ (mmHg)

42 _[37–47]

45 _[40–50]

0,127

pH

7,42 _{[7,40 – 7,44]}

7,42 _{[7,39 – 7,45]}

0,450

FEV₁ (%pv)

32 _{[25,7 – 44,2]}

34 _[27,2–46]

0,424

FEV₁/FVC

47 _{[39,7 – 55,2]}

45,8 _{[39,0 – 54,8]}

0,835

TL_CO (%pv)

35 _{[26,6 – 50,5]}

32,9 _[24–43,3]

0,254

TLC (% pv)

87,35 _{[74,5 – 102,5]}

105,4 _[90–116]

< 0,001**

RV (%pv)

132,3 _[104–179]

166,25 _[138–195]

0,008*

Ad_pl level (ng/ml)

10,239,2 [5265,7-13,062,8]

11,152,232 [7549,7-19,022,8]

0,044*