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Table 3 Possible risk factors of sensitization (n = 93) and HLA mismatch (n = 53) among lung transplant recipients with/without PRA

From: The fraction of sensitization among lung transplant recipients in a transplant center in Japan

 

Total (n = 93)

PRA+ (n = 23)

PRA- (n = 70)

p-value

History of pregnant

24 (25.8%)

8 (34.8%)

16 (22.9%)

0.280

History of transfusion

84 (90.3%)

22 (95.7%)

62 (88.6%)

0.443

Prior transplanta

6 (6.5%)

0 (0.0%)

6 (8.6%)

0.331

Any episodes of acute rejection

13 (14.0%)

2 (8.7%)

11 (15.7%)

0.508

 

Total (n = 53)

PRA+ (n = 13)

PRA- (n = 40)

p-value

HLA mismatch A/B/DRb

   

0.796

mismatch 0–2

7 (13.2%)

1 (7.7%)

6 (15.0%)

 

mismatch 3–4

23 (43.4%)

6 (46.2%)

17 (42.5%)

 

mismatch 5–6

23 (43.4%)

6 (46.2%)

17 (42.5%)

 
  1. Abbreviation: PRA panel-reactive assay, HLA human leukocyte antigen
  2. aincluding solid organ transplant and hematopoietic stem cell transplantation prior to lung transplantation
  3. bthe number of mismatched HLA-A/B/DR alleles (0–6) between donors and recipient in deceased-donor transplant and the total number of mismatch alleles (0–12) were divided to half in living-donor transplant