Table 3 The allele and genotype frequency of 4 SNPs in asthmatics and controls
Gene | SNP | Genotype / Allele | Cases (n = 263) | Controls (n = 150) | P-value/Corrected p-valuea | RECb model p-value/Corrected p-valuea | DOMc model p-value/Corrected p-valuea |
|---|---|---|---|---|---|---|---|
STIP1 | rs2236647 | TT | 38(14.44%) | 29(19.33%) | 0.018/0.072 | 0.195/0.780 | 0.005/0.020 |
TC | 113(42.97%) | 78(52.00%) | |||||
CC | 112(42.59%) | 43(28.67%) | |||||
T | 189(35.93%) | 136(45.33%) | 0.008/0.032 | ||||
C | 337(64.07%) | 164(54.67%) | |||||
GLCCI1 | rs37969 | TT | 53(20.15%) | 34(22.67%) | 0.820/1.000 | 0.547/1.000 | 0.708/1.000 |
GT | 130(49.43%) | 73(48.67%) | |||||
GG | 80(30.42%) | 43(28.67%) | |||||
T | 236(44.87%) | 141(47.00%) | 0.554/1.000 | ||||
G | 290(55.13%) | 159(53.00%) | |||||
rs37972 | TT | 47(17.88%) | 28(18.67%) | ||||
TC | 121(46.01%) | 70(46.67%) | 0.952/1.000 | 0.840/1.000 | 0.766/1.000 | ||
CC | 95(36.12%) | 52(34.67%) | |||||
T | 215(40.87%) | 126(42.00%) | 0.752/1.000 | ||||
C | 311(59.13%) | 174(58.00%) | |||||
rs37973 | GG | 54(20.53%) | 36(24.00%) | 0.675/1.000 | 0.412/1.000 | 0.550/1.000 | |
GA | 128(48.67%) | 72(48.00%) | |||||
AA | 81(30.80%) | 42(28.00%) | |||||
G | 236(44.87%) | 144(48.00%) | 0.385/1.000 | ||||
A | 290(55.13%) | 156(52.00%) |