SNPs | Genetic models | Stratified by gender | Stratified by smoking status | Stratified by BMI status | Stratified by onset age of asthma | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P | OR 95%CI | P | OR 95%CI | P | OR 95%CI | P | OR 95%CI | ||||||
rs3847076 | Dom | male | 0.048* | 1.834 (1.005–3.347) | smoking | 0.018* | 2.252 (1.149–4.413) | BMI<24 | 0.004* | 1.925 (1.233–3.007) | late onset asthma | 0.063 | 1.428 (0.981–2.077) |
Rec | 0.115 | 5.656 (0.654–48.882) | 0.09 | 4.222 (0.799–22.320) | 0.12 | 2.835 (0.761–10.559) | 0.049* | 2.861 (1.006–8.134) | |||||
Add | 0.023* | 1.869 (1.091–3.202) | 0.009* | 2.168 (1.212–3.872) | 0.005* | 1.835 (1.234–2.726) | 0.023* | 1.457 (1.054–2.013) | |||||
rs2508746 | Dom | female | – | – | non-smoking | 0.014* | 0.618 (0.420–0.908) | BMI<24 | 0.027* | 0.612 (0.396–0.946) | late onset asthma | 0.016* | 0.637 (0.441–0.919) |
Rec | – | – | 0.498 | 0.737 (0.304–1.782) | 0.862 | 0.920 (0.361–2.347) | 0.419 | 0.706 (0.304–1.641) | |||||
Add | – | – | 0.022* | 0.685 (0.495–0.947) | 0.06 | 0.710 (0.496–1.015) | 0.021* | 0.696 (0.511–0.948) | |||||
rs1892953 | Dom | female | 0.548 | 1.159 (0.717–1.873) | non-smoking | 0.456 | 0.174 (0.770–1.790) | BMI<24 | 0.702 | 1.097 (0.682–1.766) | late onset asthma | 0.692 | 1.084 (0.726–1.620) |
Rec | 0.038* | 1.738 (1.031–2.927) | 0.04* | 1.615 (1.021–2.553) | 0.017* | 1.910 (1.123–3.250) | 0.017* | 1.680 (1.095–2.578) | |||||
Add | 0.108 | 1.282 (0.947–1.737) | 0.091 | 1.259 (0.964–1.644) | 0.096 | 1.297 (0.955–1.761) | 0.094 | 1.241 (0.964–1.599) | |||||
rs12278256 | Dom | female | 0.037* | 0.468 (0.229–0.955) | non-smoking | 0.023* | 0.512 (0.287–0.913) | BMI<24 | 0.033* | 0.485 (0.249–0.944) | late onset asthma | – | – |
Rec | 1 | 1 | 1 | – | – | ||||||||
Add | 0.032* | 0.465 (0.231–0.936) | 0.02* | 0.508 (0.288–0.897) | 0.028* | 0.481 (0.250–0.923) | – | – |