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Table 1 Baseline demographics and clinical characteristics on ICU admission – comparison of patients with and without histologically confirmed organizing pneumonia

From: Diagnostic yield, safety, and impact of transbronchial lung biopsy in mechanically ventilated, critically ill patients: a retrospective study

Variable All patients (n = 42) Patients with OP (n = 23) Patients without OP (n = 14) P valuea
Clinical characteristics
 Age (years) 60.5 (± 16.1) 66.0 (± 15.4) 63.4 (± 18.8) 0.876c
 Gender (male) 26 (61.9) 13 (56.5) 9 (64.3) 0.645d
 APACHE II (points) 20.2 (± 6.4) 19.6 (± 6.3) 19.9 (± 7.2) 0.887b
 Albumin (g/dL) 2.2 (± 0.7) 2.3 (± 0.8) 2.0 (± 0.5) 0.082c
 Vasopressors 28 (66.7) 16 (69.6) 9 (64.3) 0.054d
 Hemodialysis 6 (14.3) 4 (17.4) 1 (7.1) 0.383d
 Surgery prior to ARF 12 (28.6) 10 (43.5) 2 (14.3) 0.084e
 Berlin ARDS criteria fulfilled* 25 (59.5) 15 (65.2) 9 (64.3) 0.955d
Mild (P/F 200–300) 2 (8.0) 2 (13.3) 0 (0.0)
Moderate (P/F 100–200) 19 (76.0) 11 (73.3) 7 (77.8)
Severe (P/F < 100) 4 (16.0) 2 (13.3) 2 (22.2)
 ECLA 8 (19.0) 4 (17.4) 4 (28.6) 0.445e
Cause of respiratory failure
 Pneumonia 22 (52.4) 12 (52.2) 8 (57.1) 0.772d
 AE–ILD 8 (19.0) 4 (17.4) 3 (21.4) 1.000e
 Surgery 7 (16.7) 5 (21.7) 2 (14.3) 0.687e
 Other 5 (11.9) 2 (8.7) 1 (7.1) 1.000e
Comorbidities
 CCI (points) 5.1 (± 2.5) 5.2 (± 2.1) 4.7 (± 3.1) 0.476c
 Diabetes mellitus 10 (23.8) 5 (21.7) 4 (28.6) 0.705e
 Chronic kidney disease 10 (23.8) 7 (30.4) 3 (21.4) 0.710e
 Coronary artery disease 10 (23.8) 5 (21.7) 3 (21.4) 1.000e
 Immunosuppression 7 (16.7) 4 (17.4) 3 (21.4) 1.000e