Table 2 Organ dysfunction, SOFA score, and clinical outcomes in the high and low ADA groups
High ADA (≥40 IU/L) (n = 156) | Low ADA (< 40 IU/L) (n = 36) | p-value | |
|---|---|---|---|
Organ dysfunction (SOFA score ≥ 1) | |||
Respiratory | 24 (15.4%) | 13 (36.1%) | 0.004 |
Coagulation | 2 (1.3%) | 4 (11.1%) | 0.002 |
Liver | 14 (9.0%) | 7 (19.4%) | 0.070 |
Cardiovascular | 3 (1.9%) | 7 (19.4%) | < 0.001 |
CNS | 3 (1.9%) | 4 (11.1%) | 0.008 |
Renal | 23 (14.7%) | 13 (36.1%) | 0.003 |
SOFA score | 0.68 (±1.24) | 2.31 (±2.34) | < 0.001 |
0 | 102 (65.4%) | 8 (22.2%) | |
1–2 | 41 (26.3%) | 14 (38.9%) | |
3–4 | 8 (5.1%) | 9 (25.0%) | |
5–6 | 5 (3.2%) | 3 (8.3%) | |
≥ 7 | 0 (0.0%) | 2 (5.6%) | |
Number of organs involved | < 0.001 | ||
0 | 102 (65.4%) | 8 (22.2%) | |
1 | 41 (26.3%) | 16 (44.4%) | |
2 | 11 (7.1%) | 7 (19.4%) | |
≥ 3 | 2 (1.3%) | 5 (13.9%) | |
ED visit | 97 (62.2%) | 30 (83.3%) | 0.016 |
ICU stay | 15 (9.6%) | 10 (27.8%) | 0.004 |
Death (≤30 days) | 4 (2.6%) | 5 (13.9%) | 0.004 |