Table 1 Characteristics of immunophenotypically different fibroblast subtypes in adult mouse lungs
From: CD248 and integrin alpha-8 are candidate markers for differentiating lung fibroblast subtypes
Type of fibroblast | Culture cell morphology | Proliferation | Adipocyte differentiation | Cd248 expression | ITGA8 expression | Col1a1 expression | Eln expression | Localization in mouse lung |
|---|---|---|---|---|---|---|---|---|
Sca-1high | Spindle | Rapid | + | High | Low | High | Low | Collagen fiber-rich connective tissue |
Sca-1low | Flat | Slow | – | Low | High | Low | High | Elastic fiber-rich connective tissue |