Fig. 2

Chest CT on 2019 and microscopic examination of specimens. a, b Chest CT on March 2019 showed rapid progress, disseminated thin-walled cystic lesions and nodules in bilateral lungs. c, d The pathology revealed poorly differentiated adenocarcinoma and vascular tumor emboli. e, f Pulmonary nodules diminished, and the cysts fused bizarrely shaped cysts after 1 month of afatinib therapy