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Table 3 Prognostic factors associated with the mortality of AECOPD patients readmitted within 6 months

From: The association of delta neutrophil index with the prognosis of acute exacerbation of chronic obstructive pulmonary disease

Variables

Univariate (mortality)

Multivariate (mortality)

95% CI

HR

P-value

95% CI

HR

P-value

Demographic

 GOLD group C-D

1.195, 3.549

2.060

0.009*

0.792, 2.863

1.506

0.212

 Smoking amounts, py

0.995, 1.024

1.009

0.218

   

 Long-term oxygen therapy

0.261, 0.775

0.450

0.004*

0.303, 1.107

0.580

0.098

 Readmission ≤30 d

6.679, 27.005

13.430

< 0.001*

4.554, 13.632

7.879

< 0.001*

Functional & laboratory

 Post-bronchodilator FEV1

0.977, 1.003

0.990

0.120

   

 WBC, /μL

1.000, 1.000

1.000

0.085

   

 DNI, %

1.064, 1.133

1.098

< 0.001*

1.043, 1.131

1.086

< 0.001*

 hs-CRP, mg/dL

1.003, 1.048

1.025

0.029*

0.978, 1.032

1.005

0.736

  1. *Indicates significance in univariate and multivariate analysis (P < 0.05)
  2. AECOPD acute exacerbations of chronic obstructive pulmonary disease, CI confidence interval, DNI delta neutrophil index, d days, GOLD Global Initiative for Chronic Obstructive Lung Disease, FEV1 forced expiratory volume in 1 s, hs-CRP high sensitive C-reactive protein, HR hazard ratio, py pack-years, WBC white blood cell