Fig. 3

Representative pulmonary histology from the rat model of MCT-induced PAH. Sections from all animals from treatment groups ‘No MCT’, ‘MCT Only’, NTP42, Sildenafil and Selexipag were stained with haematoxylin and eosin (H&E) and were digitally scanned using the Aperio ScanScope XT system. a Representative photomicrographs of general lung architecture are shown from a randomly selected animal from each treatment group. Images shown were captured at 200× magnification. b Representative photomicrographs, with a focus around vascular beds, from a randomly selected animal from each treatment group. Images shown were captured at 400× magnification. Black scale lines represent 50 μm