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Table 4 MCID estimates for the EQ-5D utility index and anchor

From: Validity of EQ-5D utility index and minimal clinically important difference estimation among patients with chronic obstructive pulmonary disease

 

Estimated value for MCID

Anchor

MCID

(95% CI)

Correlation coefficienta

2–3 CAT total score changes

0.021–0.031

(0.018–0.035)

0.651

8 EQ-VAS score changes

0.033

(0.027–0.040)

0.581

5–10% FEV1 predicted changes

0.017–0.033

(0.012–0.042)

0.422

The pooled MCID estimateb

0.028

(0.023–0.034)

NA

  1. MCID minimal clinically important differences, CI confidence interval, FEV1 forced expiratory volume in 1 s
  2. aThe relevance of each anchor to the EQ-5D utility index was computed as Spearman’s rank correlation coefficient
  3. bthe pooled estimation was calculated as weighted mean using the correlation coefficient between the EQ-5D utility index and each anchor
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BMC Pulmonary Medicine

ISSN: 1471-2466

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