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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: Attenuation of intermittent hypoxia-induced apoptosis and fibrosis in pulmonary tissues via suppression of ER stress activation

Fig. 2

ER stress activation in pulmonary tissue after exposure to 4 weeks of intermittent hypoxia (IH). The expression levels of Grp78 (a) and CHOP (b) in whole pulmonary tissue homogenates were detected by Western blot. Grp78 and CHOP were upregulated after 4 weeks of IH treatment, which were prevented by the injection of TUDCA (n = 4). The expression of Grp78 (c) and CHOP (d) mRNA in pulmonary tissue was increased after 4 weeks of IH treatment (n = 4).. *P < 0.05; **P < 0.01; ***P < 0.001; ns P > 0.05

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