Table 3 Efficacy results

Trough FEV₁ at Day 42, L^a

n = 42

n = 20

 LS mean change (SE)

0.24 (0.03)

−0.02 (0.04)

 Difference vs. placebo (95% CI)

0.26 (0.17, 0.36)

–

Rescue medication use Weeks 1–6, number of occasions/day^b

n = 37

n = 16

 LS mean change (SE)

−0.50 (0.15)

−0.33 (0.24)

 Difference vs. placebo (95% CI)

−0.17 (− 0.75, 0.42)

–

CAT score at Day 42^b

n = 35

n = 18

 LS mean change (SE)

−1.86 (0.78)

−0.11 (1.14)

 Difference vs. placebo (95% CI)

−1.75 (−4.54, 1.04)

–

SGRQ score at Day 42^b

n = 34

n = 18

 LS mean change (SE)

−3.13 (1.79)

−1.48 (2.62)

 Difference vs. placebo (95% CI)

−1.65 (− 8.13, 4.84)

–