Table 3 Mean value of St. George’s Respiratory Questionnaire score according to treatment outcomes over time
Total score | Symptoms score | Activity score | Impacts score | |||||
|---|---|---|---|---|---|---|---|---|
Mean (95% CI) | P-value | Mean (95% CI) | P-value | Mean (95% CI) | P-value | Mean (95% CI) | P-value | |
Microbiologic cure | ||||||||
At treatment initiation | 33.9 (26.9–40.9) | 47.0 (38.9–55.1) | 35.1 (25.4–44.8) | 28.5 (20.2–36.8) | ||||
1 year after treatment initiation | 20.8 (13.5–28.2) | < 0.001 | 28.1 (19.4–36.9) | < 0.001 | 22.8 (12.6–33.1) | 0.010 | 15.7 (7.0–24.5) | 0.002 |
2 years after treatment initiation | 21.3 (14.0–28.7) | < 0.001 | 31.3 (22.8–39.9) | 0.001 | 23.0 (12.9–33.1) | 0.009 | 17.8 (9.1–26.4) | 0.008 |
3 years after treatment initiation | 17.6 (9.1–26.1) | < 0.001 | 31.4 (20.9–41.9) | 0.007 | 21.1 (9.3–33.0) | 0.015 | 17.1 (6.9–27.3) | 0.023 |
Treatment failure | ||||||||
At treatment initiation | 36.1 (29.8–42.5) | 51.7 (44.4–59.1) | 37.9 (29.1–46.7) | 36.1 (28.5–43.6) | ||||
1 year after treatment initiation | 23.1 (16.6–29.5) | < 0.001 | 36.3 (28.8–43.7) | < 0.001 | 26.9 (18.0–35.8) | 0.007 | 19.0 (11.3–26.6) | < 0.001 |
2 years after treatment initiation | 25.0 (17.8–32.2) | 0.001 | 42.6 (33.9–51.4) | 0.054 | 28.0 (18.0–38.1) | 0.035 | 24.0 (15.4–32.7) | 0.003 |
3 years after treatment initiation | 30.4 (21.2–39.5) | 0.184 | 55.0 (43.1–66.8) | 0.616 | 31.5 (18.5–44.5) | 0.319 | 26.8 (15.6–38.0) | 0.096 |